Comparison of apparent diffusion coefficient and relative apparent diffusion coefficient values for differential diagnosis of breast lesions

Objectives: The purpose the study was to evaluate role of diffusion weighted magnetic resonance imaging (DW-MRI) in diagnosis benign and malignant breast lesions, calculate a cut-off apparent coefficient (ADC) value explore use relative ADC (r ADC) for improving sensitivity specificity MRI cancer. Methods: This retrospective based on cohort patients who underwent dynamic contrast enhanced (DCE)-MRI having suspicious mass by ultrasonography mammography whom DWI sequence added routine diagnostic MRI. r (lesion/normal tissue) values masses were calculated. threshold used differentiate lesions determined using receiver operating characteristic analysis, sensitivity, specificity, positive predictive negative Results: Malignant had significantly lower (mean: 1.03 ± 0.36 × 10-3 mm2/s) 0.66 0.22 than those with 1.50 0.56 10−3 0.97 0.31 values, respectively (p = 0.001 both). best lesion 1.09 mm2/s 72.73%, 79.17%. 0.83 78.79% 70.83%. Conclusions: has high differentiating lesions. can improve accuracy